The Senate voted Tuesday to move forward with a debate on health care reform, even though it was not clear what measure the body would be considering.

Susan Collins from Maine and Lisa Murkowski from Alaska were the only two Republican senators who voted no on the motion to proceed.

Before the voting began, protesters chanted “Kill the bill” and “Shame! Shame!”

Sen. John McCain, R-Ariz., who was diagnosed with brain cancer last week, returned to the Senate floor to vote in favor of moving the debate forward. His appearance was met with a standing ovation.