The Orange County Fire Authority says the Nissan Altima hit a center divider early Sunday, soared into the air and plowed into the top floor of the two-story structure in Santa Ana.
Photos show the sedan's front half wedged inside the building while the back half hangs about 10 feet above a sidewalk.
Officials say a small fire injured one person who managed to get out of the car unassisted. Authorities had to rescue the second person.